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标题：Sampling criteria for identifying human biomonitoring chemical differences in the Canadian Arctic
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作者：Meredith S. Curren ; Karelyn Davis ; Jay Van Oostdam 等
期刊名称：International Journal of Circumpolar Health
印刷版ISSN：1239-9736
电子版ISSN：2242-3982
出版年度：2014
卷号：73
DOI：10.3402/ijch.v73.23467
语种：English
摘要：Human biomonitoring studies in the Canadian Arctic have measured a wide range of metals and persistent organic pollutants in Aboriginal and non-Aboriginal mothers during two time periods in the Northwest Territories and Nunavut. This analysis provides preliminary estimates on sample sizes and sampling frequencies required to measure significant changes in maternal blood concentrations for PCB 153 and total mercury. For example, sample sizes of 35–40 mothers permit the detection of a 40% decrease in these chemical concentrations between two groups (e.g. communities or regions). Improvements in method sensitivity can be achieved by on-going sampling over multiple time periods (e.g. 4 or 5) in these regions, or increasing sample sizes.Keywords: Arctic; Inuit; human biomonitoring; persistent organic pollutants; mercury; Canada(Published: 17 February 2014)Citation: Int J Circumpolar Health 2014, 73: 23467 - http://dx.doi.org/10.3402/ijch.v73.23467
关键词：Arctic; Inuit; human biomonitoring; persistent organic pollutants; mercury; Canada