摘要:Dr. Grant seems to assume that all humans share the same vitamin D metabolism, an assumption that is doubtful even on theoretical grounds (1). We know that natural selection can alter the way the human body synthesises, transports and uses this vitamin. We also know that the relevant selection pressures (from solar UV and skin color) vary from one human population to the next. So it is not necessarily unhealthy for a population to have low blood levels of vitamin D. The underlying metabolism may simply be different.(Published: 24 April 2012)Citation: Int J Circumpolar Health 2012, 71: 18435 - http://dx.doi.org/10.3402/ijch.v71i0.18435