文章基本信息

标题：De Bruijn Graph based De novo Genome Assembly
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作者：Khan, Mohammad Ibrahim ; Kamal, Md Sarwar
期刊名称：Journal of Software
印刷版ISSN：1796-217X
出版年度：2014
卷号：9
期号：8
页码：2160-2168
DOI：10.4304/jsw.9.8.2160-2168
语种：English
出版社：Academy Publisher
摘要：The Next Generation Sequencing (NGS) is an important process which assures inexpensive organization of vast size of raw sequence data set over any traditional sequencing systems or methods. Various aspects of NGS like template preparation, sequencing imaging and genome alignment and assembly outlines the genome sequencing and alignment .Consequently, deBruijn Graph (dBG) is an important mathematical tool that graphically analyzes how the orientations are constructed in groups of nucleotides. Basically, de Bruijn graph describe the formation of the genome segments in a circular iterative fashions. Some pivotal de Bruijn graph based de novo algorithms and software package like T-IDBA, Oases, IDBA-tran, Euler, Velvet, ABySS, AllPaths, SOAPdenovo and SOAPdenovo2 have illustrated here.Next Generation Sequencing (NGS), deBruijn Graph (dBG), SOAPdenove2
关键词：Next Generation Sequencing (NGS);deBruijn Graph (dBG); SOAPdenove2