文章基本信息

标题：Enhancing probiotic stability in industrial processes
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作者：Miguel Gueimonde ; Borja Sánchez
期刊名称：Microbial Ecology in Health and Disease
印刷版ISSN：1651-2235
出版年度：2012
卷号：23
期号：0
DOI：10.3402/mehd.v23i0.18562
语种：English
出版社：Microbial Ecology in Health and Disease
摘要：Background: Manufacture of probiotic products involves industrial processes that reduce the viability of the strains. This lost of viability constitutes an economic burden for manufacturers, compromising the efficacy of the product and preventing the inclusion of probiotics in many product categories. Different strategies have been used to improve probiotic stability during industrial processes. These include technological approaches, such as the modification of production parameters or the reformulation of products, as well as microbiological approaches focused on the strain intrinsic resistance. Among the later, both selection of natural strains with the desired properties and stress-adaptation of strains have been widely used. Conclusion: During recent years, the knowledge acquired on the molecular basis of stress-tolerance of probiotics has increased our understanding on their responses to industrial stresses. This knowledge on stressresponse may nowadays be used for the selection of the best strains and industrial conditions in terms of probiotic stability in the final product.Keywords: probiotics; Lactobacillus; Bifidobacterium; stability; viability(Published: 18 June 2012)Citation: Microbial Ecology in Health & Disease 2012, 23: 18562 - http://dx.doi.org/10.3402/mehd.v23i0.18562
关键词：probiotics; Lactobacillus; Bifidobacterium; stability; viability