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标题：Defining microbiota for developing new Probiotics
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作者：Maria Carmen Collado ; Christine Bäuerl ; Gaspar Pérez-Martínez 等
期刊名称：Microbial Ecology in Health and Disease
印刷版ISSN：1651-2235
出版年度：2012
卷号：23
期号：0
DOI：10.3402/mehd.v23i0.18579
语种：English
出版社：Microbial Ecology in Health and Disease
摘要：The human body harbors complex communities of microbes that play a prominent role in human health. Detailed characterization of the microbiota in the target population forms the basis of probiotic use. Probiotics are defined as live bacterial preparations with clinically documented health effects in humans and independently of their genus and species, probiotic strains are unique and their beneficial properties on human health have to be assessed in a case-by-case manner. Understanding the mechanisms by which probiotics influence microbiota would facilitate the use of probiotics for both, dietary management and reduction in risk of specific diseases. The development of high throughput sequencing methods has allowed metagenomic approaches to study the human microbiome. These efforts are starting to generate an inventory of bacterial taxons and functional features bound to particular health or disease status that allow inferring aspects of the microbiome's function. In the future, this information will allow the rational design of dietary interventions aimed to improve consumer’s health via modulation of the microbiota.Keywords: microbiota; probiotic; diet; health(Published: 18 June 2012)Citation: Microbial Ecology in Health & Disease 2012, 23: 18579 - http://dx.doi.org/10.3402/mehd.v23i0.18579
关键词：microbiota; probiotic; diet; health