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标题：Use of Novel Culture Media to Indicate Alkaligenic Properties of Dental Plaque
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作者：Charlotte A. Smith ; Michael Venning ; Joanna Verran 等
期刊名称：Microbial Ecology in Health and Disease
印刷版ISSN：1651-2235
出版年度：2004
卷号：16
期号：1
DOI：10.3402/mehd.v16i1.7955
语种：English
出版社：Microbial Ecology in Health and Disease
摘要：An increase in plaque acidogenicity predisposes an individual to caries; however, caries susceptibility might also relate to a low or reduced ability to produce alkali. The aim of this study was to evaluate microbiological culture media developed in our laboratories, indicating the alkali-producing ability of plaque microorganisms. Test subjects were a group of renal failure patients (n=12) with high salivary urea levels, a control healthy population (n=14) and a small caries-free group (n=3). Solid indicator media revealed that plaque from renal patients had a higher proportion of alkaligenic microorganisms than plaque from the other test populations (p<0.05). The same samples were also more alkaligenic in urea broth (p<0.005). Neither liquid nor solid media indicative of plaque acidogenicity demonstrated significant differences between groups (p>0.05). The ability of the alkaligenic media developed in this study to reflect the known properties of the test population support its use as a simple indicator of plaque alkaligenicity, and potentially caries susceptibility, for example, when monitoring the effect of dietary alterations on plaque properties.Key words: alkaligenicity, acidogenicity, pH, plaque, renal impairment, urea.