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标题：Effect of Lactulose on the Composition and Metabolic Activity of the Human Faecal Flora
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作者：A. Terada ; H. Hara ; M. Kataoka 等
期刊名称：Microbial Ecology in Health and Disease
印刷版ISSN：1651-2235
出版年度：1992
卷号：5
期号：1
DOI：10.3402/mehd.v5i1.7768
语种：English
出版社：Microbial Ecology in Health and Disease
摘要：The effect of dietary supplementation with lactulose (3 g/d for 2 wk) on the faecal flora and faecal bacterial metabolism was studied in eight healthy volunteers. During the intake of lactulose, the number of bifidobacteria increased significantly (P < 0.01), whereas the numbers of lecithinase-positive clostridia, including Clostridium perfringens, and Bacteroidaceae decreased (P < 0.05) compared to values before and after the intake. Faecal indole, skatol and phenols, and faecal β-glucuronidase, nitroreductase and azoreductase activities were decreased significantly (P < 0.05) after 7-14 d of treatment. Mean faecal pH decreased from 7.0 to 6.4, and water content increased 3.5-5.3 per cent during lactulose ingestion.Keywords: Lactulose; Faecal flora; Faecal bacterial metabolism.