文章基本信息

标题：Evaluation of the predictive capability of an in-vitro model of colonisation resistance to Clostridium difficile infection
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作者：S. P. Borriello ; F. E. Barclay ; A. R. Welch 等
期刊名称：Microbial Ecology in Health and Disease
印刷版ISSN：1651-2235
出版年度：1988
卷号：1
期号：1
DOI：10.3402/mehd.v1i1.7394
语种：English
出版社：Microbial Ecology in Health and Disease
摘要：Caecal emulsions prepared from hamsters pre-treated with clindamycin or ampicillin supported growth of, and cytotoxin production by, Clostridium difficile, whereas those from aztreonam or temocillin pre-treated or untreated hamsters did not. These findings were predictive of outcome of infection with C. difficile as clindamycin and ampicillin pre-treated animals became colonized and died whereas the other animals did not.Keywords: Colonisation resistance; C. difficile; Antibiotic-associated colitis.