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标题：Effect of Preventing Coprophagy on Colonisation by Segmented Filamentous Bacteria in the Small Bowel of Mice
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作者：H. L. B. M. Klaasen ; J. P. Koopman ; P. M. Scholten 等
期刊名称：Microbial Ecology in Health and Disease
印刷版ISSN：1651-2235
出版年度：1990
卷号：3
期号：2
DOI：10.3402/mehd.v3i2.7518
语种：English
出版社：Microbial Ecology in Health and Disease
摘要：Segmented filamentous bacteria (SFBs) are present in the small intestine of mice and rats. It is not clear whether this presence is due to a stable colonisation or to reinfection by coprophagy. To answer this question the effect of preventing coprophagy on SFBs was studied in mice. Two parameters were determined as general indicators for a normal microecological state of the small intestine: the relative caecal weight and the percentage of caecal fusiform shaped bacteria. Prevention of coprophagy executed by means of a polyethylene ‘restrainer’ and a wire mesh resulted in a slight increase in the colonisation of SFBs (significant in small intestine section 8; p < 0.012). The number of SFBs per 100 bacteria showed an increase in section 8 compared to mice with a restrainer, but which were housed on sawdust (p < 0.032). No effects were seen on the relative caecal weight and the percentage of fusiform shaped bacteria in the caecum.Keywords: Intestinal bacteria; Colonisation; Mouse.