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  • 标题:Synthesis and Antifungal Activity of Some New Guanidines
  • 本地全文:下载
  • 作者:Puran Chandra Joshi ; P. C. Joshi
  • 期刊名称:Defence Science Journal
  • 印刷版ISSN:0976-464X
  • 出版年度:2014
  • 卷号:29
  • 期号:4
  • 页码:159-162
  • DOI:10.14429/dsj.29.6512
  • 语种:English
  • 出版社:Defence Scientific Information & Documentation Centre
  • 摘要:The synthesis of some N-subsituted -N'-aryl-N"-ethyl/benzyl guanidines (II) and (III) and their precurser thiocarbamides (I) has been carried out. All these compounds have been screened in vitro for their antifungal activity against Helminthosporium oryzae, Drechlere papendor fii and Alternaria alternata. In general, N-substituted-N'aryl-N"benzyl guanidines except N-(p-pyrolidinopropoxyphenyl)-N'-p-tolyl-N"-benzyl guanidine possess high antifungal activity against all the test fungi at concentration 2% and comparatively less at 0.2% None of these compounds exhibit fungicidal activity at lower concentrations (0.02 and 0.002%).
  • 关键词:Helminthosporium oryzae;Drechlere papendor
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