出版社:Defence Scientific Information & Documentation Centre
摘要:In this paper four 1-methyl-3-arylpropane-1, 3-diones, 1methy1-3-(3'4'-dichlorophenyl)-methyl1-3-(2-chloro-5'-methylphenyl)-1-methyl-3-(a-naphthyl)-, 1-methyl1-3-(5'6'7'8'-tetrahydro-naphth-2'-yl)propane-1,3-diones have been synthesised and coupled with different diazotised sulphonamide bases in presence of sodium acetate to give the corresponding 1-methyl-3-aryl-2- (N-substituted p-sulphamylbenezeneazo) propane-1, 3-diones. These azo compounds have been tested in vitro for their antibacterial properties against S. aureus, E.coli and p. pyocyanea and were found to possess considerable activity.