文章基本信息

标题：Electron Microscopical Study on Skin Lesions Induced by Sulphur Mustard
本地全文：下载
作者：R. S. Chauhan ; L.V.R. Murthy
期刊名称：Defence Science Journal
印刷版ISSN：0976-464X
出版年度：2013
卷号：46
期号：1
页码：15-19
DOI：10.14429/dsj.46.4039
语种：English
出版社：Defence Scientific Information & Documentation Centre
摘要：Mustard gas or sulphur mustard (SM) was applied on the dorso-caudal surface of mice to examine the effect of SM on the collagenous extracellular matrix (ECM) of the mouse skin. The animals were sacrificed on first, third and sixth days to study structural changes in the ECM of the mouse skin. Disruption of ordered arrangement of collagen bundles was observed on different days. The bundles of collagen fibres were found opened up into small fragments on the third day post-exposure. Infiltration of polymorphonuclear cells and damage to the wall surrounding the blood vessels were observed. Reformation of ordered layers of collagen bundles and the narrowing of voids were taken as indicators of recovery which became perceptible on the sixth day after exposure.
关键词：Collagen bandles ;Collagenous extracellular matrix (ECM) ;Dorso caudal;Mustard gas