文章基本信息

标题：Protective Role of Verapamil against Organophosphorus Ester Induced Delayed Neurotoxicity (Short Communication)
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作者：S. K. Dighe ; A. B. Nashikkar ; Mr. Purnanand 等
期刊名称：Defence Science Journal
印刷版ISSN：0976-464X
出版年度：2013
卷号：47
期号：2
页码：173-176
DOI：10.14429/dsj.47.3992
语种：English
出版社：Defence Scientific Information & Documentation Centre
摘要：The protective efficacy of a well-known calcium channel blocker, Verapamil, against Mipafox, a prototype of nerve gas, has been investigated. Mipafox is a potent organophosphorus ester which has both acute and delayed neurotoxic effects. The results of the present study indicate that as an adjunct to Atropine, Verapamil shows protective action in overcoming the delayed neurotoxic effects. However, it makes either little or no contribution to the recovery of the acute toxic effects of Mipafox.
关键词：Neurotoxic effects;Atropine;Mipofox