文章基本信息

标题：An in-silico analysis showing the interaction of FAD ligand with cytokinin dehydrogenase enzyme and with its domain part in rice
本地全文：下载
作者：Pranati Swain ; Lambodar Behera
期刊名称：Computational Molecular Biology
电子版ISSN：1927-5587
出版年度：2014
卷号：4
期号：15
DOI：10.5376/cmb.2014.04.0015
语种：English
出版社：Sophia Publications
摘要：The cytokinin dehydrogenase enzyme plays an important role in the high grain production of rice. This enzyme interacts with the FAD ligand. This study shows the domain region of the enzyme which was identified by protparam tool, generated homology models using modeller9.12 tool, models were validated using errat, procheck saves server, prosa and anolea server. Then the active sites were predicted by using castP server. Finally the interaction was studied between the FAD and cytokinin dehydrogenase and with its domain part. The stronger interaction was found between the FAD and the domain of the cytokinin degydrogenase with the binding enegy of -10.91. ALA6, ARG1, AR536, TYR10, ASP55, ALA57, CYS38 of FAD is binding to the domain part of cytokinin degydrogenase in rice.
关键词：FAD Ligand; Cytokinin dehydrogenase enzyme; Interaction between ligand and enzyme; Functional domain