This study aimed to estimate the prevalence of impact of oral health conditions on physical and psychosocial dimensions among adolescents and to identify factors associated with severity of impact. The impact of oral health status was assessed by the instrument Oral Health Impact Profile (OHIP-14). The covariates were: socioeconomic status, habits and health care, use of dental services, and normative conditions of oral health. Structural equation modeling was performed, and 15.6% of adolescents reported impact in at least one dimension of the OHIP-14. The dimensions that showed the highest prevalence of impact were psychological distress (11.8%) and physical pain (6.6%). The number of teeth needing dental treatment, number of filled teeth, and CPI significantly affected severity of impact. In this adolescent population, unfavorable socioeconomic conditions were associated with reduced use of dental services, associated in turn with precarious oral health conditions and increased severity of impact.