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标题：Corticosterone plasma concentrations in Carioca High- and Low-conditioned freezing rats after a fear conditioned task
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作者：LAURA ANDREA LEÓN A ; VITOR CASTRO GOMES ; MARCUS LIRA BRANDÃO 等
期刊名称：Avances en Psicología Latinoamericana
印刷版ISSN：0738-6729
出版年度：2013
卷号：31
期号：1
页码：279-287
语种：English
出版社：Universidad del Rosario
摘要：Our group in the Psychology Department at Pontifícia Universidade Católica do Rio de Janeiro (PUC-Rio) developed a rat genetic model of extreme freezing in response to contextual cues in an experimental chamber previously associated with footshock. One of the lines, Carioca High Freezing (CHF), exhibits an enhanced conditioned freezing response, whereas the other line, Carioca Low Freezing (CLF), shows the opposite res - ponse. The present study investigated corticosterone concentration between these two lines of animals and a random (RND) line of rats both under basal conditions and test condition after an emotional challenge using a contextual fear conditioning protocol. Comparisons bet - ween basal and test plasma corticosterone concentrations suggested differential basal and fear-induced differences between the two lines. The differences between basal conditions is an important and relevant aspect to be considered in behavioral experiments using or assessing stress and could help to understand variability in naïve populations.
其他摘要：Our group in the Psychology Department at Pontifícia Universidade Católica do Rio de Janeiro (PUC-Rio) developed a rat genetic model of extreme freezing in response to contextual cues in an experimental chamber previously associated with footshock. One of the lines, Carioca High Freezing (CHF), exhibits an enhanced conditioned freezing response, whereas the other line, Carioca Low Freezing (CLF), shows the opposite res - ponse. The present study investigated corticosterone concentration between these two lines of animals and a random (RND) line of rats both under basal conditions and test condition after an emotional challenge using a contextual fear conditioning protocol. Comparisons bet - ween basal and test plasma corticosterone concentrations suggested differential basal and fear-induced differences between the two lines. The differences between basal conditions is an important and relevant aspect to be considered in behavioral experiments using or assessing stress and could help to understand variability in naïve populations.
关键词：Anxiety traits; corticosterone; fear; rats Rasgos de ansiedad; corticosterona; miedo; ratas. Traço de ansiedade; corticosterona; medo; ratos.