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标题：Aspects of ingestion transmission of chagas disease identified in mummies and their coprolites
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作者：Arthur C. Aufderheide ; Wilmar Salo ; Michael Madden 等
期刊名称：Chungara, Revista de Antropología Chilena
印刷版ISSN：0716-1182
电子版ISSN：0717-7356
出版年度：2005
卷号：37
期号：1
页码：85-90
语种：English
出版社：Universidad de Tarapacá
摘要：El estudio molecular del tejido blando de 283 de cuerpos momificados en forma natural proveniente de la costa del sur de Perú y norte de Chile revela la presencia de Tripanosoma cruzi a partir de 9.000 años atrás con una prevalencia de un 41%. Este valor es parecido a áreas de estas regiones donde la enfermedad era endémica, antes que se iniciaran los programas de control de la salud. Este ensayo discute la presencia de ADNa de T. cruzi en los coprolitos de momias y revisa los posibles mecanismos de estos parásitos en los coprolitos. La presencia de T. cruzi en los coprolitos de momia no necesariamente indica que hubo una ingesta de este parásito.
其他摘要：Molecular study of Trypanosoma cruzi (T. cruzi) anciant DNA (aDNA) in the soft (nonskeletal) tissues of 283 naturally (spontaneously) mummified bodies from coastal sites located in southern Peru and northern Chile demonstrated a Chagas disease prevalence rate of about 41% over the past 9,000 years. This rate is similar to that of several endemic areas within this region prior to initiation of public health control programs. This report focuses on the presence of T. cruzi aDNA in the coprolites of some of these mummies. Review of the possible mechanisms that may explain the presence of this parasite in the coprolites indicates numerous antemortem and postmortem circumstances that conceivably could have been responsible. In given conditions, all of these may need to be considered. These considerations indicate that the presence of T. cruzi aDNA in mummy coprolites cannot categorically be considered as evidence of ingestion of the parasite.
关键词：coprolites; aDNA; american trypanosomiasis;coprolitos; ADNa; tripanosomiasis americana