文章基本信息

标题：Le piège de la maladie d'Alzheimer à présentation dysexécutive
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作者：Aurélia Poujois ; Armand Perret-Liaudet ; Catherine Thomas-Antérion 等
期刊名称：Revue de Neuropsychologie Neurosciences Cognitives et Cliniques
印刷版ISSN：2101-6739
电子版ISSN：2102-6025
出版年度：2010
卷号：2
期号：1
页码：28-31
DOI：10.1684/nrp.2010.0071
出版社：John Libbey Eurotext
摘要：Figures See all figures Authors Aurélia Poujois , Armand Perret-Liaudet , Catherine Thomas-Antérion Unité de neuropsychologie-CM2R, CHU Nord, 42055 Saint-Étienne Cedex 02, Service de neurologie, CHU Nord, 42055 Saint-Étienne Cedex 02, Centre de biologie et de pathologie Est, Groupement hospitalier Est, 69677 Bron Cedex Key words: Alzheimer disease, executive functions, cerebrospinal fluid -Amyloid 42 and tau proteins, biomarkers DOI : 10.1684/nrp.2010.0071 Page(s) : 28-31 Published in: 2010 Executive functions could be impaired very early in Alzheimer disease course and go with memory changes and aphaso-apraxo-agnosia syndrome. Difficulties may be subtle, resulting in changes in performance and strategies often offset by the subjects and rarely mentioned. When marked, this frontal dysfunction should raise the issue of differential diagnosis such as mixed dementia. The classical situation remains that of associated vascular lesions but other clinical situations like sleep apnoea, alcoholism or severe depression should be sought.
关键词：Alzheimer disease; executive functions; cerebrospinal fluid -Amyloid 42 and tau proteins; biomarkers