摘要:Authors D. Tchelougou , D.S. Karou , A. Kpotsra , A. Balaka , M. Assih , M. Bamoke , G. Katawa , K. Anani , J. Simpore , C. de Souza École supérieure des techniques biologiques et alimentaires (ESTBA-UL), université de Lomé, Lomé, Togo, Faculté mixte de médecine et de pharmacie (FMMP), université de Lomé, BP 1515, Lomé, Togo, Centre de recherche biomoléculaire Pietro Annigoni (Cerba/Labiogene), université de Ouagadougou, Ouagadougou, Burkina Faso Key words: bacterial vaginosis, pregnancy, Togo DOI : 10.1684/mst.2013.0142 Page(s) : 49-54 Published in: 2013 Objective: The aim of this study was to evaluate the prevalence of the major microorganisms causing vaginal infections in pregnant women consulting at the Regional Hospital of Sokodé and to assess their sensitivity to antibiotics. Materials andMethods: This prospective study took place from June 2010 through August 2011 and included 302 pregnant women from whom a sample was taken by a vaginal swab. Samples were processed for parasitic, bacterial, and fungal agents, by microscopic examination and culture. Results: We isolated 273 germs, alone or in association in 221 women. These germs were distributed as follows: Gardnerella vaginalis (55.31%), Candida spp (30.77%), Staphylococcus aureus (5.49%), Enterobacteriaceae (4.40%), Trichomonas vaginalis (3.66%) and Mobiluncus spp (0.37%). No Streptococcus strain was isolated during the study. Over 40% of women had bacterial vaginosis and 23.08% of them were coinfected. The occurrence of coinfection was statistically influenced by the stage of pregnancy (P = 0.05). The susceptibility tests revealed that S. aureus developed a strong resistance to aminopenicillins (66.67%) and cephalosporins (>44.44%), while Enterobacteriaceae was resistant to cephalosporins and quinolones. (16.67%). Conclusion: This study showed that pregnant women in Sokode are still exposed to vaginal infection, caused mostly by G. vaginalis and Candida species. These results underline the need for at least one vaginal swab culture for each woman during pregnancy.