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标题：Endocrine disrupters and human health: A non-exhaustive review
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作者：Sophie Desmots ; Catherine Brulez ; Emmanuel Lemazurier 等
期刊名称：Environnement, Risques & Santé
印刷版ISSN：1635-0421
电子版ISSN：1952-3398
出版年度：2005
卷号：4
期号：3
页码：195-204
出版社：John Libbey Eurotext
摘要：Figures See all figures Authors Sophie Desmots , Catherine Brulez , Emmanuel Lemazurier Laboratoire de toxicologie expérimentale, Institut national de l’environnement industriel et des risques (INERIS), Parc technologique ALATA, BP 2, 60550 Verneuil en Halatte Key words: DNA/methylation, endocrine system, health, risk assessment, xenobiotics Page(s) : 195-204 Published in: 2005 Over the past two decades, concerns about the potential health and ecological impacts of exposure to endocrine-disrupting chemicals have led to the establishment of new multi-stakeholder research and testing initiatives, committees, expert groups, newsletters, databases, etc., throughout the world. These activities have generated both new data and scientific controversies, which range from the definition and detection of “endocrine disrupters” to whether they are the cause of the adverse effects observed in wildlife and assumed in humans. Despite the lack of scientific consensus, this wave of activity has significantly advanced our understanding of the scope and magnitude of risks posed by endocrine-disrupting compounds. In this article, we review this knowledge and show that many genuine uncertainties remain and key questions continue to go unanswered.
关键词：DNA/methylation; endocrine system; health; risk assessment; xenobiotics