文章基本信息

标题：Screening for the potential probiotic yeast strains from raw milk to assimilate cholesterol
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作者：Li-Shui Chen ; Ying Ma ; Jean-Louis Maubois 等
期刊名称：Dairy Science & Technology
印刷版ISSN：1958-5586
电子版ISSN：1958-5594
出版年度：2010
卷号：90
期号：5
页码：537-548
DOI：10.1051/dst/2010001
语种：English
出版社：EDP Sciences
摘要：Consumption of dairy products containing probiotics with cholesterol-lowering activity has been proposed as a means to lower serum cholesterol. In the present work, 19 yeast strains, isolated from raw milk, were tested to obtain potential probiotic yeasts for assimilating cholesterol. During in vitro tests, 17 yeast strains were capable of growth in bile salt solutions, and most of the yeast strains tolerated low pH, surviving in gastric juice. Among the 19 strains assessed, Geotrichum sp. BY2 and Pichia kudriavzevii BY10 showed highest adhesive ability to HT-29 cells. All yeast strains were able to assimilate cholesterol in the range of 3.6–44.4% over a 72 h incubation, and seven of the yeast strains were significantly higher at assimilating cholesterol (P < 0.05). According to these results, the yeast strains P. fermentans BY5, P. kudriavzevii BY10, P. kudriavzevii BY15 and Yarrowia lipolytica HY4 may serve as potential probiotics to assimilate cholesterol in the human intestine.
关键词：yeast; probiotic; raw milk; cholesterol; 酵母; 益生菌; 原料乳; 同化胆固醇; levure; probiotique; lait cru; cholestérol