首页    期刊浏览 2024年11月30日 星期六
登录注册

文章基本信息

  • 标题:Current status of human papillomavirus vaccines
  • 本地全文:下载
  • 作者:Kim, Kwang Sung ; Park, Shin Ae ; Ko, Kyung-Nam
  • 期刊名称:Clinical and Experimental Vaccine Research
  • 印刷版ISSN:2287-3651
  • 出版年度:2014
  • 卷号:3
  • 期号:2
  • 页码:168-175
  • DOI:10.7774/cevr.2014.3.2.168
  • 语种:English
  • 出版社:KoreaMed Synapse
  • 摘要:

    Cervical cancer is a malignant neoplasm arising from cells that originate in the cervix uteri. It is the second most prevalent cancer among women. It can have several causes; an infection with some type of human papillomavirus (HPV) is the greatest risk factor for cervical cancer. Over 100 types of HPVs have been identified, and more than 40 types of HPVs are typically transmitted through sexual contact and infect the anogenital region. Among these, a number of HPVs types, containing types 16 and 18, are classified as "high-risk" HPVs that can cause cervical cancer. The HPVs vaccine prevents infection with certain species of HPVs associated with the development of cervical cancer, genital warts, and some less common cancers. Two HPVs vaccines are currently on the global market: quadrivalent HPVs vaccine and bivalent HPV vaccine that use virus-like particles as a vaccine antigen. This review discusses the current status of HPVs vaccines on the global market, clinical trials, and the future of HPVs vaccine development.

  • 关键词:Papillomavirus vaccines; Virus-like particle vaccines; Uterine Cervical Neoplasms; Clinical Trial
国家哲学社会科学文献中心版权所有