首页    期刊浏览 2024年12月11日 星期三
登录注册

文章基本信息

  • 标题:Clinical characteristics of Kawasaki disease with sterile pyuria
  • 本地全文:下载
  • 作者:Choi, Ja Yun ; Park, Sun Young ; Choi, Kwang Hae
  • 期刊名称:Korean Journal of Pediatrics
  • 印刷版ISSN:1738-1061
  • 出版年度:2013
  • 卷号:56
  • 期号:1
  • 页码:13-18
  • DOI:10.3345/kjp.2013.56.1.13
  • 语种:English
  • 出版社:The Korean Pediatric Society
  • 摘要:Purpose

    Kawasaki disease (KD) is a systemic vasculitis and affects many organ systems. It often presents sterile pyuria, microscopic hematuria, and proteinuria due to renal involvement. The aims of this study were to define clinical characteristics of acute KD patients with pyuria and to analyze meaning of pyuria in KD.

    Methods

    The medical records and laboratory findings including serum and urine test of 133 patients with KD admitted to Yeungnam University Hospital from March 2006 to December 2010 were reviewed retrospectively.

    Results

    Forty patients had sterile pyuria and their clinical characteristics including age, gender and body weight were not significantly different with those who did not have pyuria. Fever duration after treatment was significantly longer in KD patients with pyuria. Erythrocyte sedimentation rate, C-reactive protein and serum concentration of alanine aminotransferase were significantly higher in patients with pyuria. Hyponatremia and coronary artery lesion were seen more often in patients with pyuria but there was no significant difference. Also serum blood urea nitrogen was significantly higher in KD patients with pyuria. Urine β2-microglobulin was elevated in both patients groups and showed no difference between two groups.

    Conclusion

    We found more severe inflammatory reaction in KD patients with pyuria. We also found elevation of some useful parameters like β2-microglobulin that indicate renal involvement of KD through the urine test. Careful management and follow up will need for KD patients with pyuria and it is necessary in the future to study the specific parameters for renal involvement of KD.

  • 关键词:Kawasaki disease; Sterile pyuria
国家哲学社会科学文献中心版权所有