文章基本信息

标题：Incidence of New Choroidal Neovascularization in Fellow Eyes of Patients Treated for Age-Related Macular Degeneration
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作者：Lee, Jung Jin ; Lew, Young Ju ; Cho, Sung Won 等
期刊名称：Journal of the Korean Ophthalmological Society
印刷版ISSN：0378-6471
出版年度：2013
卷号：54
期号：10
页码：1534-1539
DOI：10.3341/jkos.2013.54.10.1534
语种：Korean
出版社：The Korean Ophthalmological Society
摘要：Purpose
To investigate the development of new choroidal neovascularization in fellow eyes of patients treated for unilateral exudative age-related macular degeneration (AMD).
Methods
Three hundred fourteen patients who were first diagnosed with unilateral exudative AMD and treated with intravitreal bevacizumab or ranibizumab were studied retrospectively.
Results
New exudative AMD developed in 7.0% of fellow eyes after 1 year, 10.8% after 2 years and 13.7% after more than 2 years. According to the subtype of exudative AMD, there were no significant differences between classic CNV, occult or minimally classic CNV, and PCV in the incidence of new exudative AMD. After 2 years, a higher conversion rate was found in the bevacizumab-treated group than the ranibizumab-treated group.
Conclusions
The cumulative incidence of involvement in fellow eyes with exudative AMD was 13.7% over 2 years.
关键词：Bevacizumab; Exudative age-related macular degeneration; Incidence; Ranibizumab