文章基本信息

标题：A Case Report of Intractable Scleritis Effectively Treated with Infliximab
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作者：Kim, Dong Hyun ; Wee, Won Ryng ; Lee, Jin Hak 等
期刊名称：Journal of the Korean Ophthalmological Society
印刷版ISSN：0378-6471
出版年度：2008
卷号：49
期号：10
页码：1690-1695
DOI：10.3341/jkos.2008.49.10.1690
语种：Korean
出版社：The Korean Ophthalmological Society
摘要：Purpose
To report a case of a patient with intractable scleritis with conventional immunosuppressive therapy who showed effective treatment with infliximab.
Case summary
A 71-year-old man presented with orbital cellulitis and diffuse anterior scleritis of his left eye. Although orbital cellulites showed remission with topical and systemic antibiotics, scleritis persisted despite a combination therapy of immunosuppressive agents (cyclosporin, mycophenolate, prednisolone) for 1 month. Finally, he was given infliximab (5 mg/kg) intravenously three times at 2-week intervals, after which ocular pain, chemosis, conjunctival injection, and sclera thickening considerably reduced, and scleritis completely remitted.
Conclusions
The administration of Infliximab seems to be an effective therapy in patients with intractable scleritis undergoing conventional therapy.
关键词：Infliximab; Scleritis; TNF-a