文章基本信息

标题：Dilution and slow injection reduces the incidence of rocuronium-induced withdrawal movements in children
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作者：Shin, Young Hee ; Kim, Chung Su ; Lee, Jong-Hwan 等
期刊名称：Korean Journal of Anesthesiology
印刷版ISSN：2005-6419
出版年度：2011
卷号：61
期号：6
页码：465-469
DOI：10.4097/kjae.2011.61.6.465
语种：English
出版社：The Korean Society of Anesthesiologists,
摘要：Background
The aim of this study was to evaluate whether slow injection of diluted rocuronium could reduce rocuronium-induced withdrawal movements effectively in children.
Methods
After loss of consciousness, rocuronium 0.6 mg/kg was administered into 171 children according to the pre-assigned groups as follows: Group CF, injection of non-diluted rocuronium over 5 seconds; Group CS, injection of non-diluted rocuronium over 1 minute; Group DF, injection of diluted rocuronium (10 times) over 5 seconds; Group DS, injection of diluted rocuronium over 1 minute. An investigator who was blind to the injection techniques recorded patient movements followed by rocuronium injection.
Results
The incidence of withdrawal movement in Group CF was highest among the groups (all P < 0.0001). Moreover, withdrawal movement was less frequently observed in Group DS than in Groups CS and DF (P = 0.021 and P = 0.007, respectively).
Conclusions
Slow injection of diluted rocuronium reduced the incidence of withdrawal movements in children.
关键词：child; injections; intravenous; Movement; Pain; rocuronium