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  • 标题:Anesthesia of a dental patient with Angelman syndrome -A case report-
  • 本地全文:下载
  • 作者:Kim, Bo Sung ; Yeo, Jin Seok ; Kim, Si Oh
  • 期刊名称:Korean Journal of Anesthesiology
  • 印刷版ISSN:2005-6419
  • 出版年度:2010
  • 卷号:58
  • 期号:2
  • 页码:207-210
  • DOI:10.4097/kjae.2010.58.2.207
  • 语种:English
  • 出版社:The Korean Society of Anesthesiologists,
  • 摘要:

    Angelman syndrome is characterized by a partial deficit of paired autosomal chromosome 15, which contains a subunit of the GABA (Gamma-Amino Butyric Acid) receptor. Many drugs that act on the CNS (Central Nerve System) during anesthesia are believed to exert their effects via the GABA receptors. We describe the anesthesia of a 7 year-old female patient with Angelman syndrome who underwent surgery for dental caries. The basic factors that needed to be considered when administering anesthesia to this patient were epilepsy, significant dominance of the vagal tone, craniofacial abnormalities and peripheral muscular atrophy. Inhalational anesthetics (sevoflurane) were employed for this patient. The patient had an uneventful peri-operative period and was discharged home on the same day of the operation.

  • 关键词:anesthesia; Angelman syndrome; Chromosome 15; GABA receptor; Outpatient surgery
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