文章基本信息

标题：Dynamic Characteristics of the Hippocampal Neuron under Conductance’s Changing
本地全文：下载
作者：Yueping Peng ; Nan Zou ; Haiying Wu 等
期刊名称：International Journal of Information Engineering and Electronic Business
印刷版ISSN：2074-9023
电子版ISSN：2074-9031
出版年度：2011
卷号：3
期号：1
页码：38-44
出版社：MECS Publisher
摘要：The hippocampal CA1 pyramid neuron has plenty of discharge actions. In the thesis, the dynamic characteristics of the hippocampal neuron model are analyzed and discussed by the neurodynamic theory and methods. Under a certain amplitude current’s stimulation, the change of gNa(the maximum conductance of the transient sodium channel) and gKdr (the maximum conductance of the delay rectification potassium channel) can cause different dynamic characteristics of the neuron model. The transient Na+ current(INa ) caused by gNa is indispensable in the discharge’s formation process of the model. The model can generate the discharge process only when gNa reaches a certain threshold. In the discharge process of the neuron model, gNa’s changing affects little and the ISIs approximate to a straight line. The delay rectification K+ current(Ikdr) caused by gKdr isn’t indispensable in the discharge’s formation process of the model. But gKdr’s changing affects much in the discharge process of the neuron model. With gKdr’s changing, the neuron model undergoes different dynamic bifurcation process, and has plenty of discharge patterns such as the chaos, period, and so on. This investigation is helpful to know and investigate the dynamic characteristics and the bifurcation mechanism of the hippocampal neuron; and it provides a certain theory assist to investigate the neural diseases such as the Alzheimer disease by neurodynamics.
关键词：Neuron;neurodynamics;conductance