文章基本信息

标题：Antimicrobial Properties of Penicillium Species Isolated from Agricultural Soils of Northern Iran
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作者：E. Gharaei-Fathabad ; M.A. Tajick-Ghanbary ; N. Shahrokhi 等
期刊名称：Research Journal of Toxins
印刷版ISSN：1819-3560
电子版ISSN：2151-7258
出版年度：2014
卷号：6
期号：1
页码：1-7
DOI：10.3923/rjt.2014.1.7
出版社：Academic Journals Inc., USA
摘要：As a part of a research program that aimed to identify antibacterial and antifungal substances from fungus specimen of North Iranian soil samples, four penicillium species were identified as a source of secondary metabolites possessing antibiotic activities. These microorganisms were cultured in a liquid medium for 10 days. The antimicrobial disc assay activity of these extracts towards Candida albicans, Bacillus subtillis , Staphylococcus aureus , Salmonella typhi and Escherichia coli was performed. Supernatants and cell extracts of P. viridicatum Westling, P. citrinum Thom., P. aurantiogriseum Dierckx and P. waksmanii Zaleski showed distinguished antimicrobial activities. TLC assay of supernatants and cell extracts showed production of citrinin by P. citrinum and P. aurantiogriseum and penicillic acid by P. viridicatum and P. aurantiogriseum ; while two unknown metabolites from P. waksmanii needed more examinations. These mycotoxins could be examined for other biological activities such as antineoplastic property.