文章基本信息

标题：Effect of Acalypha wilkesiana on Activities of Some Liver Function Enzymes and Body Weight of Normal Rabbits
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作者：Omage Kingsley ; Erifeta O. Georgina ; Josiah J. Sunday 等
期刊名称：Pakistan Journal of Nutrition
印刷版ISSN：1680-5194
电子版ISSN：1994-7984
出版年度：2011
卷号：10
期号：6
页码：552-554
DOI：10.3923/pjn.2011.552.554
出版社：Asian Network for Scientific Information
摘要：The effects of Acalypha wilkesiana leaves on serum ALT and AST activities and body weight of normal rabbits were investigated. Oral administration of the leaf, in the form of decoction prepared by mixing 5 g of air-dried powdered leaves in 10 ml distilled water, at a dose of 1 g/kg body weight for a period of 8 and 15 days, caused a significant increase (p<0.05) in the activities of serum ALT and a significant decrease (p<0.05) in AST activities in normal rabbits. The treatment also led to a significant reduction (p<0.05) on the body weight of the experimental animals. This effect of the plant is a reflection of the relative safety of the plant in the management of hypertension and its possible use as a weight reduction therapy.