文章基本信息

标题：Comparison of dexmedetomidine and midazolam in prevention of myoclonus occurring due to etomidate in coronary bypass surgery
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作者：Nevriye Salman ; Hasan Alper Gurbuz ; Huseyin Oguzalp 等
期刊名称：Journal-Cardiovascular Surgery
电子版ISSN：2147-6535
出版年度：2013
卷号：1
期号：3
页码：52-56
DOI：10.5455/jcvs.2013133
出版社：International Medical Journal Management and Indexing System
摘要：Objectives: Etomidate is frequently employed in patients with unstable hemodynamics due its low cardiopulmonary side effects. Besides the common side effects, myoclonus induced by etomidate is a serious problem. Several agents were proposed for inhibition of myoclonus, but they were not compared. In this study we aimed to compare the efficacy of dexmedetomidine and midazolam in etomidate induced myoclonus. Materials and Methods: Sixty patients undergoing elective coronary bypass surgery were prospectively randomized into two groups. Patients in group D were administered dexmedetomidine and in group M received midazolam prior to etomidate use. Sedation, pain in the injection site and myoclonus were evaluated by scoring systems. Results: The preoperative demographic characteristics of the patients were comparable in two groups. Sedation scores were lower in dexmedetomidine group (p
关键词：Myoclonus; etomidate; dexmedetomidine; midazolam