文章基本信息

标题：Amino acid supplementation and impact on immune function in the context of exercise
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作者：Vinicius Fernandes Cruzat ; Maurício Krause ; Philip Newsholme 等
期刊名称：Journal of the International Society of Sports Nutrition
电子版ISSN：1550-2783
出版年度：2014
卷号：11
期号：1
页码：61
DOI：10.1186/s12970-014-0061-8
语种：English
出版社：BioMed Central
摘要：Moderate and chronic bouts of exercise may lead to positive metabolic, molecular, and morphological adaptations, improving health. Although exercise training stimulates the production of reactive oxygen species (ROS), their overall intracellular concentration may not reach damaging levels due to enhancement of antioxidant responses. However, inadequate exercise training (i.e., single bout of high-intensity or excessive exercise) may result in oxidative stress, muscle fatigue and muscle injury. Moreover, during the recovery period, impaired immunity has been reported, for example; excessive-inflammation and compensatory immunosuppression. Nutritional supplements, sometimes referred to as immuno-nutrients, may be required to reduce immunosuppression and excessive inflammation. Herein, we discuss the action and the possible targets of key immuno-nutrients such as L-glutamine, L-arginine, branched chain amino acids (BCAA) and whey protein.
关键词：Immunonutrition ; L-glutamine ; L-arginine ; L-leucine ; Oxidative stress