文章基本信息

标题：Modeling Physical and Chemical Growths of Avascular Tumor
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作者：Changyu Liu1 ; Huiling Li ; Alex Hauptmann 等
期刊名称：International Journal of Multimedia and Ubiquitous Engineering
印刷版ISSN：1975-0080
出版年度：2014
卷号：9
期号：4
页码：349-362
DOI：10.14257/ijmue.2014.9.4.36
出版社：SERSC
摘要：Due to the avascular tumor growths were a complex activities that involved a chemical process and a physical process, a Finite Element Method (FEM) based mixture model was proposed in this paper. For the chemical process, the FEM was used to solve the reaction diffusion equations of three chemicals, which are the oxygen, glucose and GIF, under several specified boundary conditions. For the physical process, the FEM was used to solve the total energy equations which can be uniquely calculated as a function of the nodal displacements in the tumor. In each simulation step, we minimize the energy increment for all the tumor cells. The experiment results demonstrated that the proposed approach is quite efficient for the modeling of avascular tumor growth.
关键词：Finite Element; mixture model; tumor growth; physical; chemical