Collaborative emergency management mode provides a new idea for further reducing system safety risk in the chemical park. In this paper, the cloud computing and the expert system were used for the framework design of the emergency management information system to enhance emergency response capability of collaborative emergency managementmechanisms. The use of middleware integrated with multi-source data achieved the unified data manipulation interface. Intelligent delivery of information system was provided. Using agent-middleware technology to build decision layer could make massive data analysis, data mining and decision from the “cloud computing” platform access for every user. It can provide the necessary theoretical and technical support for enterprises in the chemical park, to give full play to the collaborative emergency management capability.