文章基本信息

标题：Alitretinoin for the treatment of severe chronic hand eczema
本地全文：下载
作者：Thomas King ; John McKenna ; Anton B Alexandroff 等
期刊名称：Patient Preference and Adherence
印刷版ISSN：1177-889X
电子版ISSN：1177-889X
出版年度：2014
卷号：8
页码：1629-1634
DOI：10.2147/PPA.S38830
出版社：Dove Medical Press Ltd
摘要：Chronic hand eczema is a common and often debilitating condition. Alitretinoin, a 9- cis -retinoic acid and pan-retinoic acid agonist, is a new and effective systemic treatment for chronic hand eczema, which provides another treatment option. A “clear” or “almost clear” response can be achieved in up to half of patients within a 24-week course of treatment. Even higher rates of remission can be obtained with a longer duration of treatment. Alitretinoin has a favorable overall profile of adverse effects; however, female patients who are at risk of becoming pregnant should follow a strict pregnancy-prevention program due to the teratogenic effects of this drug.
关键词：dermatitis; toctino; CTCL