文章基本信息

标题：Relevance of Chronic Lyme Disease to Family Medicine as a Complex Multidimensional Chronic Disease Construct: A Systematic Review
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作者：Liesbeth Borgermans ; Geert Goderis ; Jan Vandevoorde 等
期刊名称：International Journal of Family Medicine
印刷版ISSN：2090-2042
电子版ISSN：2090-2050
出版年度：2014
卷号：2014
DOI：10.1155/2014/138016
出版社：Hindawi Publishing Corporation
摘要：Lyme disease has become a global public health problem and a prototype of an emerging infection. Both treatment-refractory infection and symptoms that are related to Borrelia burgdorferi infection remain subject to controversy. Because of the absence of solid evidence on prevalence, causes, diagnostic criteria, tools and treatment options, the role of autoimmunity to residual or persisting antigens, and the role of a toxin or other bacterial-associated products that are responsible for the symptoms and signs, chronic Lyme disease (CLD) remains a relatively poorly understood chronic disease construct. The role and performance of family medicine in the detection, integrative treatment, and follow-up of CLD are not well studied either. The purpose of this paper is to describe insights into the complexity of CLD as a multidimensional chronic disease construct and its relevance to family medicine by means of a systematic literature review.