文章基本信息

标题：Control of malaria and other vector-borne protozoan diseases in the tropics: enduring challenges despite considerable progress and achievements
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作者：Denis Zofou ; Raymond B Nyasa ; Dickson S Nsagha 等
期刊名称：Infectious Diseases of Poverty
印刷版ISSN：2049-9957
出版年度：2014
卷号：3
期号：1
页码：1
DOI：10.1186/2049-9957-3-1
语种：English
出版社：BioMed Central
摘要：Vector-borne protozoan diseases represent a serious public health challenge, especially in the tropics where poverty together with vector-favorable climates are the aggravating factors. Each of the various strategies currently employed to face these scourges is seriously inadequate. Despite enormous efforts, vaccines—which represent the ideal weapon against these parasitic diseases—are yet to be sufficiently developed and implemented. Chemotherapy and vector control are therefore the sole effective attempts to minimize the disease burden. Nowadays, both strategies are also highly challenged by the phenomenon of drug and insecticide resistance, which affects virtually all interventions currently used. The recently growing support from international organizations and governments of some endemic countries is warmly welcome, and should be optimally exploited in the various approaches to drug and insecticide research and development to overcome the burden of these prevalent diseases, especially malaria, leishmaniasis, Human African Trypanosomiasis (HAT), and Chagas disease.
关键词：Malaria ; Vector-borne protozoan diseases ; African trypanosomiasis ; Chagas disease ; Leishmaniasis ; Vector control ; Chemotherapy ; Vaccine development