文章基本信息

标题：Effects of vitamin D in the elderly population: current status and perspectives
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作者：Olivier Bruyère ; Etienne Cavalier ; Jean-Claude Souberbielle 等
期刊名称：Archives of Public Health
印刷版ISSN：0778-7367
电子版ISSN：0778-7367
出版年度：2014
卷号：72
期号：1
页码：32
DOI：10.1186/2049-3258-72-32
语种：English
出版社：BioMed Central
摘要：Besides its well-known effect on bone metabolism, recent researches suggest that vitamin D may also play a role in the muscular, immune, endocrine, and central nervous systems. Double-blind RCTs support vitamin D supplementation at a dose of 800 IU per day for the prevention of falls and fractures in the senior population. Ecological, case–control and cohort studies have suggested that high vitamin D levels were associated with a reduced risk of autoimmune diseases, type 2 diabetes, cardio-vascular diseases and cancer but large clinical trials are lacking today to provide solid evidence of a vitamin D benefit beyond bone health. At last, the optimal dose, route of administration, dosing interval and duration of vitamin D supplementation at a specific target dose beyond the prevention of vitamin D deficiency need to be further investigated.
关键词：Fracture Prevention ; Fall Prevention ; Other Hand ; Lower Extremity Strength ; Senior Population