文章基本信息

标题：Confronting diversity in the production of clinical evidence goes beyond merely including under-represented groups in clinical trials
本地全文：下载
作者：Karien Stronks ; Nicolien F Wieringa ; Anita Hardon 等
期刊名称：Trials
印刷版ISSN：1745-6215
电子版ISSN：1745-6215
出版年度：2013
卷号：14
期号：1
页码：177
DOI：10.1186/1745-6215-14-177
语种：English
出版社：BioMed Central
摘要：There is increasing evidence that outcomes of health care differ by patient characteristics, such as gender and ethnicity. If evidence-based medicine is to improve quality of care for all patients, it is essential to take this diversity into account when designing clinical studies. So far, this notion has mainly been translated into recommendations for including minority populations in trials. We argue that a more comprehensive view of the production of diversity-sensitive clinical evidence is needed, one that takes heterogeneity as a starting point in research. We call for a mix of methodological approaches aimed at identifying diversity issues that matter and analysing the impact of these diversities on clinical outcomes. Institutional changes are necessary to support this methodological reform.
关键词：Evidence-based medicine ; Diversity ; Clinical trials