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  • 标题:When study site contributes to outcomes in a multi-center randomized trial: a secondary analysis of decisional conflict in men with localized prostate cancer
  • 本地全文:下载
  • 作者:Meghan L Underhill ; Fangxin Hong ; Donna L Berry
  • 期刊名称:Health and Quality of Life Outcomes
  • 印刷版ISSN:1477-7525
  • 电子版ISSN:1477-7525
  • 出版年度:2014
  • 卷号:12
  • 期号:1
  • 页码:159
  • DOI:10.1186/s12955-014-0159-3
  • 语种:English
  • 出版社:BioMed Central
  • 摘要:Evaluate baseline factors that may explain the influence of study site on decisional conflict (DC) in men from the Personal Patient Profile: Prostate (P3P) randomized trial. 476 cases from 5 P3P sites were included. Participants completed baseline demographic assessments, 4 subscales of the DC scale at baseline (uncertainty, informed, values clarity, and support), the Expanded Prostate Cancer Index Composite (short form) and the State-Trait Anxiety Inventory. Site data regarding typical practices were collected. Linear regressions were used to model the relation between baseline DC scores and study site adjusting for the list of variables. Baseline decisional uncertainly (p?=?0.001) and informed (p?=?0.03) subscales were significantly different across sites. Participant demographic and baseline measures were significantly different (p?
  • 关键词:Localized prostate cancer ; Decisional conflict ; Decision-making
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