文章基本信息

标题：Ingested hyaluronan moisturizes dry skin
本地全文：下载
作者：Chinatsu Kawada ; Takushi Yoshida ; Hideto Yoshida 等
期刊名称：Nutrition Journal
印刷版ISSN：1475-2891
电子版ISSN：1475-2891
出版年度：2014
卷号：13
期号：1
页码：70
DOI：10.1186/1475-2891-13-70
语种：English
出版社：BioMed Central
摘要：Hyaluronan (HA) is present in many tissues of the body and is essential to maintain moistness in the skin tissues, which contain approximately half the body’s HA mass. Due to its viscosity and moisturizing effect, HA is widely distributed as a medicine, cosmetic, food, and, recently marketed in Japan as a popular dietary supplement to promote skin moisture. In a randomized, double-blind, placebo-controlled clinical study it was found that ingested HA increased skin moisture and improved treatment outcomes for patients with dry skin. HA is also reported to be absorbed by the body distributed, in part, to the skin. Ingested HA contributes to the increased synthesis of HA and promotes cell proliferation in fibroblasts. These effects show that ingestion of HA moisturizes the skin and is expected to improve the quality of life for people who suffer from dry skin. This review examines the moisturizing effects of dry skin by ingested HA and summarizes the series of mechanisms from absorption to pharmacological action.
关键词：Hyaluronan ; Hyaluronic acid ; Ingestion ; Dry skin ; Moisturizing