文章基本信息

标题：Plant sterols as dietary adjuvants in the reduction of cardiovascular risk: theory and evidence
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作者：Craig S Patch ; Linda C Tapsell ; Peter G Williams 等
期刊名称：Vascular Health and Risk Management
印刷版ISSN：1176-6344
电子版ISSN：1178-2048
出版年度：2006
卷号：2
期号：2
页码：157-162
出版社：Dove Medical Press Ltd
摘要：Plant sterol-enriched foods are an effective dietary adjuvant in reducing cardiovascular risk by lowering total cholesterol and low density lipoprotein-cholesterol (LDLC) in serum by up to ~15%. The mechanism of action of plant sterols is different from those of 3-hydroxy-3-methylglutaryl coenzyme A inhibitors (statins) and thus their effect is additive. Combining plant sterols with other dietary components known to reduce cholesterol in a portfolio approach has proven to be most effective for reduction of hypercholesterolemia and provide an alternative treatment option for clinicians. Plant sterol-enriched foods provides clinicians with a relatively cheap, safe, and effective way to help patients manage their cardiovascular risk.
关键词：plant sterols; plant stanols; cardiovascular risk; cholesterol; LDL-cholesterol