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  • 标题:Lymphoid Enhancing Factor 1 (Lef-1) overexpression in epithelial ovarian, fallopian tube and peritoneal cancer and associations with clinical factors
  • 本地全文:下载
  • 作者:Clements, Aine ; Engle, David ; Shelton, Dawne
  • 期刊名称:Proceedings in Obstetrics and Gynecology
  • 印刷版ISSN:2154-4751
  • 出版年度:2011
  • 卷号:2
  • 期号:1
  • 页码:1-2
  • 出版社:University of Iowa
  • 摘要:Lef-1 mRNA levels were statistically elevated in cases of ovarian, fallopian tube or peritoneal cancer when compared to non-cancerous controls. Among cancer cases, levels of Lef-1 were statistically different between stage and histology. Lef-1 overexpression may be predictive of poor overall survival. These findings suggest that Lef-1 overexpression may contribute to ovarian, fallopian tube and peritoneal carcinogenesis, and that further investigation is warranted.
  • 关键词:LEF-1; ovarian cancer; fallopian tube cancer; peritoneal cancer
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