文章基本信息

标题：H19/miR-675 non-coding RNA expression differentiates among cancers of the human endometrium.
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作者：Devor, Eric J ; DeMik, Jill N. ; Schickling, Brandon M. 等
期刊名称：Proceedings in Obstetrics and Gynecology
印刷版ISSN：2154-4751
出版年度：2011
卷号：2
期号：1
页码：1-1
出版社：University of Iowa
摘要：H19 is a maternally expressed non-coding RNA located at chromosome 11p15.5 near the reciprocally imprinted insulin-like growth factor 2 (IGF2) gene. Though the function of H19 is unknown, it is transcribed during embryonic development after which transcription is absent in all but a few tissues including cardiac muscle, breast, ovary, uterus, and placenta. Linking H19, miR-675 and RB1 expression with serous tumors of the endometrium suggests that RB1 suppression may be a differentiating event in serous tumorigenesis.
关键词：endometrium; endometrial cancer; RNA