文章基本信息

标题：MicroRNAs, Cellular Behavior, and Endometrial Cancer
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作者：Devor, Eric J
期刊名称：Proceedings in Obstetrics and Gynecology
印刷版ISSN：2154-4751
出版年度：2010
卷号：1
期号：2
页码：1-15
出版社：University of Iowa
摘要：Endometrial cancer is the most common gynecological cancer and the fourth most common cancer in women worldwide. In spite of its’ relative importance to overall morbidity among women, molecular research in endometrial cancers lags far behind other cancers such as breast and colorectal. Nowhere is this more true than in research in the newly emergent field of post-transcriptional gene regulation by small, regulatory RNAs, primarily microRNAs (miRNAs). Here, structure, biogenesis, and mode of action of miRNAs is presented along with a brief overview of the role of miRNAs in carcinogenesis and a review of the few miRNA studies in endometrial cancer carried out to date.
关键词：microRNA; cancer; cellular behavior; dysregulation; endometrial cancer