文章基本信息

标题：Acute Toxicity of Four Organophosphorus Pesticides Products
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作者：Li, Peng ; Yin, Ya-ling ; Wang, Qian-qian 等
期刊名称：Journal of Food Distribution Research
印刷版ISSN：0047-245X
出版年度：2012
页码：85-88
出版社：Food Distribution Research Society
摘要：Acute toxicity of phoxim, acephate, isofenphos-methyl and isocarbophos on male SD rats of clean grade was carried out by gastric lavage method at room temperature of 18℃. These rats are 4 to 5 months old with body weight of 180 to 220 kg. The results indicate that the orders of the toxicity of these four pesticides on SD rats are isofenphos-methyl, isocarbophos, acephate, phoxim. We found that the median lethal concentration of phoxim in 24 h, 48 h, 72 h and 96 h is 3.892g/kg, 3.051 g/kg, 2.618 g/kg and 2.458g/kg respectively; the median lethal concentration of isofenphos-methyl in 24 h, 48 h, 72 h and 96 h is 0.015g/kg, 0.013g/kg, 0.012g/kg and 0.011 g/kg respectively; the median lethal concentration of isocarbophos in 24 h, 48 h, 72 h and 96 h is 0.049 g/kg, 0.046 g/kg, 0.043 g/kg, 0.041 g/kg respectively; and the median lethal concentration of acephate in 24 h, 48 h, 72 h and 96 h is 0.137 g/kg,0.113 g/kg, 0.100 g/kg,0.085 g/kg respectively. Finally, we evaluated the characteristics of toxicity effect and safe concentration of these pesticides to SD rats.
关键词：Phoxim;Acephate;Isofenphos-methyl;Isocarbophos;Acute toxicity;SD rats