文章基本信息

标题：Utility of ranolazine in chronic stable angina patients
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作者：Pawan D Patel ; Rohit R Arora
期刊名称：Vascular Health and Risk Management
印刷版ISSN：1176-6344
电子版ISSN：1178-2048
出版年度：2008
卷号：4
期号：4
页码：819-824
DOI：10.2147/VHRM.S2841
出版社：Dove Medical Press Ltd
摘要：Chronic stable angina is a debilitating illness affecting at least 6.6 million US residents. Despite being optimally treated by pharmacotherapy and revascularization up to 26% of patients still experience angina. Diabetes mellitus is a common co-morbid condition in angina patients. Several new investigational medications are being tested for chronic angina. Advances in understanding of myocardial ischemia have prompted evaluation of a number of new antianginal strategies. In this review we discuss the utility of ranolazine, a recently approved novel antianginal agent and its efficacy in the diabetic patient population. In addition to its antianginal action in diabetic patients with chronic angina, ranolazine may have favorable effects on glycated hemoglobin levels.
关键词：chronic stable angina; antianginal; ranolazine; diabetes mellitus; glycated hemoglobin