文章基本信息

标题：Surgery in current therapy for infective endocarditis
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作者：Stuart J Head ; M Mostafa Mokhles ; Ruben LJ Osnabrugge 等
期刊名称：Vascular Health and Risk Management
印刷版ISSN：1176-6344
电子版ISSN：1178-2048
出版年度：2011
卷号：7
页码：255-263
DOI：10.2147/VHRM.S19377
出版社：Dove Medical Press Ltd
摘要：The introduction of the Duke criteria and transesophageal echocardiography has improved early recognition of infective endocarditis but patients are still at high risk for severe morbidity or death. Whether an exclusively antibiotic regimen is superior to surgical intervention is subject to ongoing debate. Current guidelines indicate when surgery is the preferred treatment, but decisions are often based on physician preferences. Surgery has shown to decrease the risk of short-term mortality in patients who present with specific symptoms or microorganisms; nevertheless even then it often remains unclear when surgery should be performed. In this review we i) systematically reviewed the current literature comparing medical to surgical therapy to evaluate if surgery is the preferred option, ii) performed a meta-analysis of studies reporting propensity matched analyses, and iii), briefly summarized the current indications for surgery.
关键词：endocarditis; surgery; antibiotics; review; meta-analysis; propensity analysis; mortality; complications