文章基本信息

标题：Implications of chemokine receptors and inflammatory lipids in cancer
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作者：Johannes Rolin ; Azzam A Maghazachi
期刊名称：ImmunoTargets and Therapy
电子版ISSN：2253-1556
出版年度：2013
卷号：3
页码：9-18
DOI：10.2147/ITT.S32049
出版社：Dove Medical Press Ltd
摘要：Inflammatory lipids receive much attention due to their important biological activities. Knowledge of the chemokine system has also reached a level that makes it interesting in clinics, which prompted clinical trials into compounds manipulating chemokines or their receptors. However, little attention has been devoted to understand the relations between these two systems. Here, we will review the role of inflammatory lipids and chemokines in innate and adaptive immunity with an attempt to link the two systems and with emphasis on their importance in cancer development.
关键词：chemokines; FTY720; HODE; linoleic acid; sphingosine 1-phosphate