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标题：Circulation and antigenic drift in human influenza B viruses in SE Asia and Oceania since 2000
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作者：Ian G Barr ; Naomi Komadina ; Chris Durrant 等
期刊名称：Communicable Diseases Intelligence
印刷版ISSN：1447-4514
电子版ISSN：1445-4866
出版年度：2006
卷号：30
期号：3
页码：350-357
出版社：Government Department of Health and Ageing
摘要：During annual in. uenza epidemics, in. uenza B viruses frequently co-circulate with in. uenza A viruses and in some years, such as 2005, large outbreaks have occurred while in other years, the virus virtually disappears. Since 1987 there have been two lineages of in. uenza B viruses co-circulating in various countries and causing disease in humans. The proportions of these two lineages vary from year to year and country to country. For example, in 2005, the B/Victoria/2/87 lineage was predominant in New Zealand while in Australia the B/Yamagata/16/88 lineage was more common. Antigenic and genetic analysis has revealed gradual movement in the both lineages. Careful monitoring of the two virus line-ages is important, as they are antigenically distinct. This is an important consideration for in. uenza vaccine formulation decisions, as only one in. uenza B component is traditionally included in the annual trivalent in. uenza vaccine
关键词：In. uenza B; serology; vaccines; vaccination; phylogenetic; evolution